Scientific and Statistical Principles
Below is a collection of resources including a series of articles published in The American Journal of Clinical Nutrition offering tutorials on existing and established statistical methods for the design and analysis of nutrition-related research.
A Guide for Authors and Readers of the American Society for Nutrition Journals on the Proper Use of P Values and Strategies that Promote Transparency and Improve Research Reproducibility
Valuing the Diversity of Research Methods to Advance Nutrition Science
Resources for the Design and Conduct of Human Nutrition Randomized Controlled Trials
Introduction to the series “Best (but Oft-Forgotten) Practices”
Dennis M Bier, David B Allison, David H Alpers, Arne Astrup, Kevin D Cashman, Paul M Coates, Naomi K Fukagawa, David M Klurfeld, Richard D Mattes, Ricardo Uauy
The American Journal of Clinical Nutrition, Volume 102, Issue 2, 1 August 2015, Pages 239–240, https://doi.org/10.3945/ajcn.115.117697 Published: 15 July 2015
Best (but oft-forgotten) practices: designing, analyzing, and reporting cluster randomized controlled trials
Andrew W Brown, Peng Li, Michelle M Bohan Brown, Kathryn A Kaiser, Scott W Keith, J Michael Oakes, David B Allison
The American Journal of Clinical Nutrition, Volume 102, Issue 2, 1 August 2015, Pages 241–248, https://doi.org/10.3945/ajcn.114.105072 Published: 27 May 2015
Related Content:
Nutrition 2018 Presentation: Cluster Randomized Trials
Peng Li, PhD, Department of Biostatistics, University of Alabama Birmingham, Birmingham, Alabama
Best (but oft-forgotten) practices: checking assumptions concerning regression residuals
Lawrence E Barker, Kate M Shaw
The American Journal of Clinical Nutrition, Volume 102, Issue 3, 1 September 2015, Pages 533-539, https://doi.org/10.3945/ajcn.115.113498 Published: 01 September 2015
Best (but oft forgotten) practices: testing for treatment effects in randomized trials by separate analyses of changes from baseline in each group is a misleading approach
J Martin Bland, Douglas G Altman
The American Journal of Clinical Nutrition, Volume 102, Issue 5, November 2015, Pages 991–994, https://doi.org/10.3945/ajcn.115.119768
Related Articles:
Response to “Best (but oft forgotten) practices: testing for treatment effects in randomized trials by separate analyses of changes from baseline in each group is a misleading approach” (Kimber L Stanhope, Peter J Havel)
The American Journal of Clinical Nutrition, Volume 103, Issue 2, 1 February 2016, Pages 589, https://doi.org/10.3945/ajcn.115.125989 Published: 01 February 2016
Reply to KL Stanhope and PJ Havel (J Martin Bland, Douglas G Altman)
The American Journal of Clinical Nutrition, Volume 103, Issue 2, 1 February 2016, Pages 589, https://doi.org/10.3945/ajcn.115.125997 Published: 01 February 2016
Best (but oft-forgotten) practices: the multiple problems of multiplicity—whether and how to correct for many statistical tests
David L Streiner
The American Journal of Clinical Nutrition, Volume 102, Issue 4, 1 October 2015, Pages 721–728, https://doi.org/10.3945/ajcn.115.113548 Published: 05 August 2015
Related Content:
Nutrition 2018 Presentation: Issues in Multiple Testing
John A. Dawson, PhD, Department of Nutritional Sciences, Texas Tech University, Lubbock, TX
Best (but oft-forgotten) practices: sensitivity analyses in randomized controlled trials
Russell J de Souza, Rebecca B Eisen, Stefan Perera, Bianca Bantoto, Monica Bawor, Brittany B Dennis, Zainab Samaan, Lehana Thabane
The American Journal of Clinical Nutrition, Volume 103, Issue 1, 1 January 2016, Pages 5–17, https://doi.org/10.3945/ajcn.115.121848Published:16 December 2015
Related Content:
Nutrition 2018 Presentation: Sensitivity Analysis
Lehana Thabane, PhD, Department of Health Research Methods, Evidence, and Impact, McMaster University, Hamilton, Ontario, Canada
Best (but oft-forgotten) practices: expressing and interpreting associations and effect sizes in clinical outcome assessments
Lori D McLeod, Joseph C Cappelleri, Ron D Hays
The American Journal of Clinical Nutrition, Volume 103, Issue 3, 1 March 2016, Pages 685–693, https://doi.org/10.3945/ajcn.115.120378 Published:10 February 2016 Erratum
Best (but oft-forgotten) practices: the design, analysis, and interpretation of Mendelian randomization studies
Philip C Haycock, Stephen Burgess, Kaitlin H Wade, Jack Bowden, Caroline Relton, George Davey Smith
The American Journal of Clinical Nutrition, Volume 103, Issue 4, 1 April 2016, Pages 965–978, https://doi.org/10.3945/ajcn.115.118216 Published:09 March 2016
Best (but oft-forgotten) practices: propensity score methods in clinical nutrition research
M Sanni Ali, Rolf HH Groenwold, Olaf H Klungel
The American Journal of Clinical Nutrition, Volume 104, Issue 2, 1 August 2016, Pages 247–258, https://doi.org/10.3945/ajcn.115.125914 Published:13 July 2016
Best (but oft-forgotten) practices: intention-to-treat, treatment adherence, and missing participant outcome data in the nutrition literature
Bradley C Johnston, Gordon H Guyatt
The American Journal of Clinical Nutrition, Volume 104, Issue 5, 1 November 2016, Pages 1197–1201, https://doi.org/10.3945/ajcn.115.123315 Published:12 October 2016
Best (but oft-forgotten) practices: mediation analysis
Amanda J Fairchild, Heather L McDaniel
The American Journal of Clinical Nutrition, Volume 105, Issue 6, 1 June 2017, Pages 1259–1271, https://doi.org/10.3945/ajcn.117.152546 Published: 26 April 2017
Best (but oft-forgotten) practices: missing data methods in randomized controlled nutrition trials
Peng Li, Elizabeth A Stuart
The American Journal of Clinical Nutrition, Volume 109, Issue 3, March 2019, Pages 504–508, https://doi.org/10.1093/ajcn/nqy271 Published: 22 February 2019
Best (but oft forgotten) practices: sample size planning for powerful studies
Samantha F Anderson
The American Journal of Clinical Nutrition, Volume 110, Issue 2, August 2019, Pages 280–295, https://doi.org/10.1093/ajcn/nqz058 Published: 27 May 2019
Best (but oft-forgotten) practices: identifying and accounting for regression to the mean in nutrition and obesity research
Diana M Thomas, Nicholas Clark, Dusty Turner, Cynthia Siu, Tanya M Halliday, Bridget A Hannon, Chanaka N Kahathuduwa, Cynthia M Kroeger, Roger Zoh, David B Allison
The American Journal of Clinical Nutrition, Volume 111, Issue 2, February 2020, Pages 256–265, https://doi.org/10.1093/ajcn/nqz196 Published: 24 September 2019
Related Content:
Nutrition 2018 Presentation: Regression to the Mean
David Allison, Department of Epidemiology and Biostatistics, Indiana University School of Public Health-Bloomington, Bloomington, IN
Best (but oft-forgotten) practices: sample size and power calculation for a dietary intervention trial with episodically consumed foods
Wei Zhang, Aiyi Liu, Zhiwei Zhang, Tonja Nansel, Susan Halabi
The American Journal of Clinical Nutrition, nqaa176, https://doi.org/10.1093/ajcn/nqaa176 Published: 09 July 2020